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Using Wegovy During Pregnancy: What You Need to Know

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Using Wegovy During Pregnancy: What You Need to Know

Navigating medication safety during pregnancy is a crucial concern for expectant mothers. When it comes to weight management and the use of medications like Wegovy, understanding the risks and exploring alternatives becomes paramount. In this guide, we will delve into the question of whether it is safe to take Wegovy while pregnant, highlighting the potential risks involved and offering insights into alternative approaches to managing weight during pregnancy. Your health and the well-being of your baby are top priorities, and making informed decisions is key to ensuring a healthy pregnancy journey.

Wegovy (semaglutide) is a prescription medication used for weight management in adults with obesity or overweight. It works by decreasing caloric intake by activating receptors in the brain involved in appetite regulation. As an individual considering Wegovy, it's important to understand the implications of using this medication during pregnancy.

Wegovy and Pregnancy: The Risks

According to the patient information leaflet for Wegovy, this medication should NOT be used during pregnancy. The reason for this is that the effects of Wegovy on an unborn child are currently unknown. Exposing a developing foetus to Wegovy could potentially pose risks, though more research is needed.

It's recommended that individuals using Wegovy who wish to become pregnant should stop taking the medication at least two months before trying to conceive. This allows the medication to clear the body before a pregnancy begins. If you do become pregnant while taking Wegovy, it's crucial to inform your healthcare provider immediately so they can adjust your treatment plan accordingly.

Animal studies have raised significant concerns about the use of semaglutide during pregnancy. These studies have shown that when administered to pregnant animals at doses below the maximum recommended human dose, semaglutide can cause:

  • Embryo-foetal mortality
  • Structural abnormalities in the developing foetus
  • Alterations to foetal growth and development

Early pregnancy losses and various structural abnormalities have been observed in rabbits, monkeys, and rats exposed to semaglutide during gestation.

Based on these concerning findings from animal research, the FDA has not assigned a pregnancy category for semaglutide and advises that the medication should be discontinued if pregnancy is detected. The potential risks to the developing foetus are considered to outweigh any potential benefits of continuing Wegovy therapy during pregnancy.

Contraception and Wegovy

Healthy Pregnant Woman

Given the unknown risks of Wegovy during pregnancy, it's essential to use effective contraception while taking this medication. The patient information leaflet advises that you should use contraception to prevent pregnancy. This is an important safety measure to protect both you and your unborn child.

Don't Make Decisions Alone – Talk to Your Doctor

If you are considering Wegovy for weight management and are of childbearing age, it's crucial to have an open discussion with your healthcare provider about your plans for pregnancy. They can provide guidance on the appropriate use of Wegovy and help you make an informed decision that prioritises your health and the health of a potential future pregnancy.

Alternatives to Semaglutide During Pregnancy

Given the concerning findings from animal studies on the use of semaglutide during pregnancy, there are alternative weight management strategies that may be safer options for pregnant women.

The primary alternatives would be lifestyle-based approaches focused on diet and exercise. Working closely with your doctor, you can develop a safe and effective plan for managing weight gain during pregnancy through healthy eating habits and physical activity. This may involve things like:

  • Adopting a balanced, nutrient-dense diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats
  • Engaging in regular moderate exercise, such as walking, swimming, or prenatal yoga, as approved by your obstetrician
  • Monitoring weight gain and making adjustments to diet and exercise as needed to stay within recommended guidelines

Frequently Ask Questions

  • I'm taking Wegovy and just found out I'm pregnant. What should I do?
    Discontinue Wegovy immediately if you become pregnant and contact your healthcare provider. Animal studies show semaglutide can cause harm to the developing foetus. The FDA advises stopping Wegovy if pregnancy is detected.
  • I want to lose weight before becoming pregnant. Is it safe to take Wegovy for this?
    No, the FDA advises discontinuing Wegovy at least 2 months before a planned pregnancy due to insufficient data on its safety during human pregnancy. Animal studies raise concerns about risks to the foetus.
  • Are there any natural supplements that are safe for weight loss during pregnancy?
    The safest approach is diet and exercise under medical supervision. There is limited evidence on the safety of weight loss supplements during pregnancy, so they should be avoided without consulting your doctor.
  • If I was on Wegovy before pregnancy, will it still affect my baby?
    Discontinue Wegovy as soon as pregnancy is detected, as animal studies show concerning outcomes like increased embryo-foetal mortality and foetal abnormalities with in utero exposure. Monitor pregnancy with your healthcare provider.
  • Can I start using Wegovy again after I give birth?
    The safety of resuming Wegovy after pregnancy and during breastfeeding is unclear. Please contact your healthcare provider if you would like to start Wegovy again. 

Conclusion

In summary, Wegovy should not be used during pregnancy due to the unknown effects on the unborn child. If you are taking Wegovy and wish to become pregnant, it's recommended to stop the medication at least two months in advance and use effective contraception. By working closely with your healthcare provider, you can navigate the use of Wegovy while prioritising your reproductive health.


The information provided is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of a doctor with any questions you may have regarding a medical condition. Never delay seeking or disregard professional medical advice because of something you have read here.

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